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Our old surgery professors often reminded us of the time when the operating rooms were like ovens Oia carbolic acid fumes made the air unbreathable, where carbolic acid flooded wound dressings. Here is how Professor von Winiwarter defines the evolution antisepsis essay on old custom to asepsis No septic infection seemed possible in a wound where carbolic acid had passed. However this absolute faith was shaken when serious bacteriological research had shown that carbolic acid, employee degree usual concentration for short time relat ement, not faculty had surely kill pathogens in tissues v ants.
They then resorted to more concentrated solutions carbolic carbolic acid were replaced by more powerful antiseptic, sublimate. But when careless surgeons employed these agents prolonged contact with wound, the effects were disastrous not only their antiseptic thesis writing influence was zero, but, otherwise, result of local septic conditions often more intense chronic acute systemic poisonings, directly due to the acid carbolic sublimate. This result, paradoxical at first glance, however, easily explained.
Antiseptic substances are poisons, including microbicide action is based on their influence on albiiminoïdes protoplasm v ant microbes. However, this action easily produced in vitro reactions tube, presence of dead organic material. But when antiseptics come contact website that writes essay as you type with an infected wound microbes, destroying admission essay service their ability protoplasm v ant is exercised primarily on the cells of tissues, much less resistant than microbes, occurs a real mortification, gangrene of the tissues, action antiseptic carbolic acid solutions sublimate on microorganisms is almost canceled because these substances, by cauterizing tissues, form with albumin cells compounds having no more any effect on microorganisms. They found, contrary to the parties mortified, the best conditions to multiply, thus these breakdowns occur putrid, like hardly saw the préantiseptique time.
Present facts kind under the influence of Dr. Koch's school work, principles Lister bandage were subjected to a serious experiment, which had been lacking until now, because bacteriology not have exact investigation methods. It was found, first, that wound infection by the ambient air was of minimal importance compared with the contact infection. Therefore, a wound that had not been contact with contaminated body microbes could be considered non-infected did not need to be subjected to the action of chemical antiseptics.
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